Auxins are plant hormones governing many biological
processes in higher plants such as cell enlargement and division, differentiation
of vascular tissue, apical dominance, root initiation and signaling.
Indole-3-acetic acid (IAA, see Fig.
above) is the most commonly occurring natural auxin.
Here we present a 3D
library of auxin related compounds.
The classification of auxins and their analogues into
four classes is based on similarity analysis of their interaction properties
and measured biological activities.
References:
1. Classification
of auxin plant hormones by interaction property similarity indices,
Tomic S., Gabdoulline R. R., Kojic-Prodic B. and Wade R. C., J. Comput.
Aided Mol. Design. (1998), in press.
2. Classification
of auxin related compounds based on similarity of their interaction fields:
Extension to a new set of compounds,Tomic S., Gabdoulline R. R., Kojic-Prodic
B. and Wade R. C., Internet J. Chem, submitted for publication.