Wednesday - 4.02.2009

8:45 - Registration

Session 1 - Nucleosome

Chair: Rebecca Wade

9:15 - Introduction
9:25 - Andy Andrews (Department of Biochemistry and Molecular Biology, Colorado State University, USA)

A coupled equilibrium approach for measuring nucleosome thermodynamics

10:10 - Vladimir Teif (Group Genome Organization Function BioQuant German Cancer Research Center, Germany)

Predicting nucleosome positions on the DNA: combining intrinsic affinities and remodeler activities

10:40 - Coffee break
11:00 - Jordanka Zlatanova (Department of Molecular Biology, Wyoming University, USA)

Nucleosome dynamics: single-molecule studies

11:45 - Jrg Langowski (Deutsches Krebsforschungszentrum (DKFZ), Germany)

Coarse-grained modelling of nucleosome dynamics

12:15 - Thomas C. Bishop (Center for Computational Science, Tulane University, USA)

Development of a Nucleosome Energy Level Diagram for Chromatin Folding

13:00 - Lunch
14:00 - Poster session

Session 2 - From nucleosome towards chromatin fiber

Chair: Tomasz Wocjan

15:00 - Karsten Rippe (Research Group Genome Organization Function, BioQuant Center German Cancer Research Center (DKFZ), Germany)

Controlling DNA accessibility via the local nucleosome geometry and internucleosomal interactions

15:45 - Mithun Biswas (IWR, University of Heidelberg, Germany)

Loop formation in nucleosome with a linear elasticity model

16:15 - Coffee break
16:35 - Tamar Schlick (Dept. of Chemistry and Courant Inst. of Mathematical Sciences, New York University, USA)

Mesoscale modeling of chromatin organization

17:20 - Georgi V. Pachov (EML Research, Germany)

DNA flexibility does not affect linker histone protein binding mode

17:50 - Yaakov (Koby) Levy (Weizmann Institute of Science, Israel)

Protein sliding along DNA: Dynamics and structural characterization

18:20 - End
22:00 - 00:00 - Social events

Thursday - 5.02.2009

Session 3 - Chromatin fiber I

Chair: Jrg Langowski

9:15 - John van Noort (Institute of Physics, Leiden University, The Netherlands)

Pulling on Single Chromatin Fibers

10:00 - Thomas Hfer (DKFZ and BioQuant Center, Germany)

Stochasticity and specificity in DNA repair: a dynamic model for chromatin-associated regulatory processes

10:30 - Coffee break
10:50 - Andrew Routh (MRC Laboratory of Molecular Biology, Cambridge, England)

Chromatin higher-order structure

11:35 - Yair Field (Weizmann Institute of Science, Israel)

Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals

12:05 - Kenichi Yoshikawa (Department of Physics, Kyoto University, Japan)

Hierarchical Dynamics of Chromatin: Physical Aspects

13:00 - Lunch
14:00 - Poster session

Session 4 - Chromatin fiber II

Chair: Mithun Biswas

15:00 - Helmut Schiessel (Lorentz Institute for Theoretical Physics, Leiden University, The Netherlands)

Structure of chromatin on larger scales

15:45 - Jean-Marc Victor (CNRS, Paris, France)

Magnetic tweezers turn nucleosomes inside-out: in vitro modeling and in vivo predictions

16:15 - Coffee break
16:35 - Julien Mozziconacci (The Computer Laboratory, Cambridge University, England)

Graphical Modeling of the Beta-Globin Transcription Factory

17:20 - Lars Nordenskild (Nanyang Technological University, School of Biological Sciences, Singapore)

Counterion Induced Electrostatic Condensation and Self-Assembly of Nucleosome Core Particles (NCP) and Chromatin Arrays

17:50 - Philipp Diesinger (Institut fuer Theoretische Physik, University of Heidelberg, Germany)

The Effects of Nucleosome and Linker Histone Depletion on Properties of Chromatin: A Monte Carlo Model

18:20 - End
20:00 - Conference Dinner (Restaurant Kulturbrauerei)
22:00 - 00:00 - Social events

Friday - 6.02.2009

Session 5 - Beyond chromatin fiber

Chair: Georgi Pachov

9:15 - Peter R. Cook (The Sir William Dunn School of Pathology, Oxford University, England)

A model for all genomes: the role of transcription factories

10:00 - Ren Stehr (University of Applied Sciences Stralsund, Germany)

Dynamic numerical phase diagrams of chromatin

10:30 - Coffee break
10:50 - Dieter W. Heermann (Institute for Theoretical Physics, Heidelberg University, Germany)

The Relation between the Gene Network, Gene Expression and the Physical Structure of Chromosomes

11:35 - Evgeny Gladilin (DKFZ Heidelberg, Germany)

Contactless investigation of nuclear mechanics using a 3D image- and model-based framework

12:05 - Paul Wiggins (Whitehead Institute for Biomedical Research, Cambridge MA, USA)

Chromatin Organization in E.coli

13:00 - Lunch
14:00 - Bye-bye