Versions:

Version 1.0 was developed at EMBL, Heidelberg, Germany.

Version 2.0 was developed at EML Research gGmbH, Heidelberg, Germany.

Changes in the version 2.0 are:

•  The programs rewritten to make the parameter usage more transparent - previous parameter input from the files is changed to the input via command line;
•  Fixed subdirectory hierarchy is replaced via user-defined, e.g. calculations can be done in any chosen directory;
•  Only an upper part of the similarity matrix is calculated, thus the computations for a set of n protens are done not for n*n but n*(n+1)/2 pairs;
•  Enabled a possibility to add extra proteins to already  processed set of proteins;
•  Added phylogenic tree analysis;
•  Added APBS electrostatic potential based analysis;
•  Added several auxiliary programs.
  

Availability:

    The current version of PIPSA (Protein Interaction Property Similarity Analysis) may be downloaded from this page.