Model of Escherichia coli signal recognition particle, Ffh, created with Swiss-Model. Aligned against Ffh from Thermus aquaticus with GMPPNP (1JPJ.pdb), Ffh from Thermus aquaticus with GDP-Mg²⁺ (1NG1.pdb), Ffh from Acidianus ambivalens (1J8M.pdb), and the FtsY SRP receptor from E. coli (1FTS.pdb).

Here's the WhatCheck report for this model.

Overlayed GTP structures from mutant GTP-binding proteins found in the Protein Databank.

Secondary Structure and GTP-Mg²⁺ (one of the above possible) superimposed in E. coli Ffh.

GTP-Mg²⁺ superimposed in E. coli Ffh. Potential ligands shown: Asp189, Thr114, Asp250, Gln108, Gly109, Arg140, Arg193, Gly192, Lys112, Thr113, Lys118, Gly276.

E. coli Ffh with GTP-Mg²⁺ and E. coli FtsY with GTP-Mg²⁺ superimposed on 1N2C.pdb nitrogenase structure as proposed by I. Sinning et al.