a Macromolecular Interface Navigator
Please note the new Molsurfer implementation.
You can also access the old Molsurfer implementation (for reference and old download only).
MolSurfer can be used to study protein-protein
and protein-DNA/RNA interfaces. The 2D projections of the computed
interface aid visualization of complicated interfacial geometries in 3D.
Molecular properties, including hydrophobicity and electrostatic potential,
can be projected onto the interface. MolSurfer can thereby aid exploration
of molecular complementarity, identification of binding "hot spots" and
prediction of the effects of mutations. MolSurfer can also facilitate the
location of cavities at macromolecular interfaces.